Zetia Alternatives Compared
Zetia | Repatha | Nexlizet |
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Zetia (ezetimibe) | Repatha (evolocumab) | Nexlizet (bempedoic acid/ezetimibe) |
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Prescription only
Zetia may be used to lower cholesterol alone or in combination with a statin or fibrate. It has few reported side effects and few drug interactions. It is effective at lowering intestinal absorption... View more |
Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Nexlizet contains ezetimibe and bempedoic acid and has been shown to decrease LDL-C levels by more than either drug alone. It is usually given in combination with other cholesterol-lowering... View more |
Related suggestions High Cholesterol
High Cholesterol, Familial Heterozygous
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More about Zetia (ezetimibe) | More about Repatha (evolocumab) | More about Nexlizet (bempedoic acid/ezetimibe) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Zetia has an average rating of 4.3 out of 10 from a total of 74 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 57% reported a negative effect. |
Repatha has an average rating of 5.1 out of 10 from a total of 609 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 49% reported a negative effect. |
Nexlizet has an average rating of 8.8 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 0% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Zetia side effects in more detail. |
See also: Repatha side effects in more detail. |
See also: Nexlizet side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zetia prices |
View all Repatha prices |
View all Nexlizet prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
22 hours |
408 hours |
22 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 42 drugs are known to interact with Zetia:
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A total of 2 drugs are known to interact with Repatha:
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A total of 87 drugs are known to interact with Nexlizet:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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First Approval Date | ||||||||||||||||||||||||||
October 25, 2002 |
August 27, 2015 |
February 26, 2020 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.